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Rams vs 49ers Predictions With bet365 Promo Code LWOSBONUS

Brock Purdy will attempt to right the ship, while Matthew Stafford and company seek to play spoiler in their Rams vs 49ers division matchup.
49ers Rams Predictions

Week 3 of the NFL slate features an NFC West clash involving the Rams vs 49ers. San Fransisco’s high expectations have been under fire after injuries to stars Christian Christian McCaffrey and Deebo Samuel. The franchise will try to bounce back from a surprise loss to the Minnesota Vikings with a victory over Los Angeles.

Meanwhile, the 0-2 Rams are seeking their first win of the season. The club is also trying to find its identity in the wake of injuries to their receiver duo of Puka Nacua and Cooper Kupp.

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Rams vs 49ers Odds

  • Moneyline: Rams (+275) vs 49ers (-350)
  • Spread: Rams -7 (-110) vs 49ers +7 (-110)
  • Over/Under: Over 44.0 (-110) / Under 44.0 (-110)

Rams vs 49ers Prediction

Rams 17, 49ers 27

Matchups between offensive innovators Kyle Shanahan and Sean McVay are always entertaining. Unfortunately, the injury bug has removed several octane weapons from this matchup. However, you can be sure each side is properly motivated to earn a victory against their rival.

At the end of the day, the remaining core of Purdy, Brandon Aiyuk, and George Kittle, combined with a dangerous San Francisco defense, should have an edge over Stafford, Kyren Williams, and company. Los Angeles will attempt to produce offense through their ground game. And their home field advantage will help. But the Niners will be a touch matchup to handle.

Rams vs 49ers Best Bets

49ers win by +7 (-110)

McCaffrey in particular is a pillar of San Francisco’s success. His value to his team cannot be overstated. However, the Rams 44-10 loss to the Cardinals in week two is a clear sign that the club, particularly the defense, has major issues.

Betting the over on an injury riddled road team in a division matchup is always dangerous. But the Rams abysmal performances and comparable injury concerns give them very little margin for error.

Tyler Johnson over 33.5 Receiving Yards (-110)

The 49ers offense should get off to a fast start against this the 32nd ranked Rams defense. A blowout game script will put Stafford and company in a position where they have to throw early and often to keep pace. While their scoring production will likely be low, there are plenty of opportunities for garbage-time productions from Los Angeles receivers against the 19th ranked Niners’ pass defense.

Johnson, Demarcus Robinson, and Colby Parkinson are all good bets to eclipse their overs in receiving years. However, Johnson low mark of 33.5 low is the safest best on the board.

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Main Photo Credit: Sergio Estrada-USA TODAY Sports

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