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George Kittle Week 16 Bold Predictions Monday Night Football

December 22, 2025 By Doug Henderson Predictions

Monday Night Football Bold Predictions: Week 16 – Colts vs. 49ers

Bold Prediction 3:

Philip Rivers Bold Predictions Monday Night Football Week 16 — Colts quarterback Philip Rivers steps into a throw over the middle of the field. | Source: Lastwordonsports.com - Doug Henderson

Rivers’ inability to throw deep makes Alec Pierce struggle, and he has fewer than 25 receiving yards.

Bold Prediction 4:

San Francisco 49ers quarterback Brock Purdy (13) scrambles out of the pocket against the Arizona Cardinals at State Farm Stadium in Glendale on Nov. 16, 2025. | Source: Lastwordonsports.com - Doug Henderson

Brock Purdy shows the world he is a Super Bowl–caliber quarterback and throws for 300+ yards.

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Tags: Indianapolis Colts NFL Schedule San Francisco 49ers

About Doug Henderson

Doug Henderson grew up playing every sport imagineable. He quickly hit a ceiling his playing skills didn't let him break and had to turn to writing to get his sports fix.

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