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Use bet365 Promo Code LWOSBONUS For $200 FREE With Our Chiefs vs Chargers Predictions & Best Bets

The AFC West clash featuring the Chiefs vs Chargers has the potential for a high variance of outcomes. Superstar Patrick Mahomes leads a high powered Kansas City offense into their first matchup with new LA Head Coach Jim Harbaugh. Meanwhile, Bolts star QB Justin Herbert is nursing an ankle injury that could cause him to miss the game in favor of veteran backup Taylor Heinicke.

The Chiefs vs Chargers AFC West battle could pivot drastically depending on the Bolts injury situation.

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Chiefs vs Chargers Odds with bet365

  • Moneyline: Chiefs (-370) vs Chargers (+290)
  • Spread: Chiefs -7.0 (-115) vs Chargers +7.0 (-105)
  • Over/UnderOver 40.0 (-110) / Under 40.0 (-110)

Chiefs vs Chargers Prediction

KC Chiefs 27, LA Chargers 16

While the Chiefs running back room has suffered injuries to both Isiah Pacheco and Clyde Edwards-Helaire, the rest of their loaded roster remains relatively healthy. The mash unit of Carson Steele, Samaje Perine, and Kareem Hunt will attempt to stabilize a running game, while Mahomes utilizes the duo of Rashee Rice and Xavier Worthy. Kansas City will also strive to help star Travis Kelce emerge from his slow start to the season.

Much of the Chargers’ 2024 success will be dictated by Herbert’s ability to fulfill lofty expectations. Unfortunately for the Los Angeles, their injury concerns extend well beyond their star quarterback. Starters Joey Bosa, Otito Ogbonnia, Kristian Fulton, Ja’Sir Taylor, Joe Alt, Trey Pipkins III, Rashawn Slater, and Joshua Palmer are all listed as questionable on the club’s injury report. For context, that includes three of their five starting offense lineman, two starters in their secondary, and their best pass rusher.

If even half of these players are unavailable (or limited) it will put an already undermanned Los Angeles team at an even bigger disadvantage. This AFC West matchup will be loads of fun when both clubs are at full strength. Unfortunately, the Chargers are far from 100%.

Chiefs vs Chargers Best Bets with bet365 Promo Code

Carson Steele Over 40.5 Rushing Yards (-110)

This is largely a game script prediction. There is little reason to think the Chargers will keep the game competitive. As such the Chiefs will likely feature a heavier than normal rushing attack as they kill game clock. Perine’s best skills are as a receiver. And Hunt was recently re-added to Kanas City‘s roster. This should leave Steele in a great position to crush the over on his 40.5 rushing yards line.

Xavier Worthy Over 0.5 Rushing Yards (+115)

Using the same game script argument, this would be an ideal week for wide receiver Xavier Worthy to surpass his measly 0.5 rushing yards line. The blazing rookie already has five rushing attempts over the clubs first three games, for a total of 39 rushing yards (13 per carry).

If Head Coach Andy Reid gives Worthy even a single rushing attempt, whether it come as their Chiefs build a lead, or as they churn through the clock, he will be a lock to surpass this over.

For the record, if Herbert and the majority of his supporting cast is able to recover and play, the closer game script also yields well to more offensive ingenuity for the Chiefs. This is a smart bet under any circumstances.

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