Week 10 DraftKings Plays: Saquon Barkley, Dameon Pierce, and More

Week 10 DraftKings

Just like that, we already have nine weeks of NFL football in the books. One of my favorite parts is fantasy football. One of my favorite aspects of fantasy football has become playing on DraftKings. Every week is like a new puzzle to figure out. Whether you are more of a cash game player or a tournament player, each presents a unique challenge. Let’s take a look at my favorite Week 10 DraftKings plays.

READ MORE: Week 10 Stream Team

Week 10 DraftKings Plays

Week 9 Recap

It’s always good to be completely transparent and demonstrate accountability. That’s what I like to do with everything I do, and that also goes for fantasy football. Whether it’s bold takes or DraftKings recommendations, I always like to keep track of wins and losses. It’s not only good for the readers to know, but it also helps me learn from mistakes moving forward.

Looking back at Week 9, it was a solid week for recommendations. This week 52% of my recommendations hit the 2.5x value we look for in cash game lineups. This time the quarterback group led the way at a 100% success rate. Meanwhile, the tight end group brought up the rear at a 0% success rate. Personally, it was a profitable week. We’ll look to get it going even better with the picks and get more profits in the Week 10 DraftKings plays.

  • Week 9 – $231 → $341 ($110 PROFIT)
  • Year Total – $2,133 → $2,275 ($142 PROFIT)


Patrick Mahomes (KC) – $7,800 v JAX

It seems like a long time ago that people were questioning if Patrick Mahomes would drop off a bit due to the loss of Tyreek Hill. Ultimately he’s just as good as most people thought he was and hasn’t seen any dip in production despite losing one of the best playmakers in the NFL. Mahomes is averaging 27.7 DraftKings points per game this season which trails only Josh Allen. He’s scored over 30 points on four separate occasions now as well. Mahomes is coming off two straight 400+ yard performances and now gets a great matchup against the Jacksonville Jaguars. The Jaguars have allowed the 12th-most DraftKings points to quarterbacks so far. What’s even more exciting is the game environment. This game has the highest combined total on the slate at 50.5 points. The Kansas City Chiefs have the highest implied team total on the slate at 30 points. Expect Mahomes to keep rolling making him one of the best Week 10 DraftKings plays.

Jacoby Brissett (CLE) – $5,400 @ MIA

It’s a Jacoby Brissett revenge game so what is there not to like? On a more serious note, Brissett has actually been much more serviceable than expected so far this season. While he’s only scored more than 20 DraftKings points once this year (last week), he also has scored double-digits in every single game this season. Brissett is averaging 15.1 DraftKings points per game in 2022 and is in a great spot to top that number this week against the Miami Dolphins. The Dolphins have allowed the most DraftKings points to quarterbacks so far this season. Part of that is the fact they have a banged-up secondary but the other part is the fact they score so many points that teams are forced to throw more often. Either way, Brissett should be set up nicely in his return to Miami.

Others to Consider: Daniel Jones (NYG) – $5,700 v HOU, Justin Fields (CHI) – $6,500 v DET, Matthew Stafford (LAR) – $5,600 v ARI

Running Backs

Saquon Barkley (NYG) – $8,600 v HOU

What do you get when you mix one of the best running backs in the NFL and one of the worst defenses in the NFL? The potential for an absolutely bonkers game is the answer. Saquon Barkley is enjoying an awesome comeback season averaging 20.7 DraftKings points per game this year. That ranks fifth-best among all running backs in 2022. Barkley is one of the few workhorse running backs in the league. He ranks first in snap share (83.4%) and opportunity share (85.0%), second in carries (163), third in rushing yards (779) and route participation (60.1%), and fifth in target share (17.1%) among all running backs this year. That gives him such a high floor and ceiling combination. This week it doesn’t get better than a matchup against the Houston Texans. The Texans have been getting gashed on the ground and have allowed the most DraftKings points to running backs so far this year. Barkley is the most expensive running back on the slate but also has more upside than anyone as well with a massive floor. This makes him one of the best Week 10 DraftKings plays.

Dameon Pierce (HOU) – $6,300 @ NYG

Staying in that same game and moving to the other side is another workhorse back albeit a surprising one. Dameon Pierce garnered a lot of buzz throughout the preseason and it has turned out to be for good reason. He looks very explosive on his runs and hard to bring down. The Texans have to be happy with their find. His 30% snap share from Week 1 seems like years ago at this point. Since then Pierce has eclipsed 50% in every game and 60% in all but one game. Even more encouraging is the route participation increases. Since Week 4 he’s seen at least 40% route participation in all but one game including at least 60% in each of the last two games. He didn’t get any targets last game but with that type of route participation, the targets will come. That gives him a sneaky high floor compared to most running backs which is particularly intriguing considering he’s on the Texans and they are trailing more often than not. Pierce is averaging 16 DraftKings points per game this season. With that type of workload and production, he should be much more expensive than he currently is.

Others to Consider: Derrick Henry (TEN) – $8,300 v DEN, Alvin Kamara (NO) – $7,400 @ PIT, Travis Etienne (JAX) – $7,100 @ KC, Josh Jacobs (LV) – $7,600 v IND, Jamaal Williams (DET) – $5,900 @ CHI

Wide Receivers

Cooper Kupp (LAR) – $9,000 v ARI

Cooper Kupp is inevitable. Despite how much the Los Angeles Rams are crumbling, Kupp still stands tall as an absolute stud. Despite the struggles of Stafford and the Rams, he is still averaging 26.8 DraftKings points per game which leads all wide receivers this year. Kupp has scored at least 16 DraftKings points in every game this year and at least 22 DraftKings points in all but two games. He’s on pace to finish the season with 153 receptions, 1,727 receiving yards, and 15 touchdowns. That’s a ridiculous follow-up to an insane 2021 season, especially considering what’s going on around him. This matchup against the Arizona Cardinals is not necessarily as juicy as it looked like it would be before the year but is still good. The Cardinals are one of the fastest-paced teams in the league and can score themselves so that should help push the pace for Kupp and the Rams.

Mack Hollins (LV) – $4,200 v IND

After Mack Hollins exploded for 33 DraftKings points in Week 3 he only has 35.8 DraftKings points combined in the five games since. A lot of that is due to the Las Vegas Raiders getting healthier. Well, consider them very banged up once again as they just placed both Darren Waller and Hunter Renfrow on IR this week. That should mean much more opportunities once again for Hollins. He’s even been a bit more productive lately already scoring double-digit DraftKings points in two of his last three games. The Raiders also have a nice implied team total of 22.5 points this week. They are playing at home as well which means it will be played in a dome which should boost the outlook of the passing offenses. All of this makes Hollins one of the best Week 10 DraftKings plays especially from a point-per-dollar standpoint.

Others to Consider: Tyreek Hill (MIA) – $9,100 v CLE, Amon-Ra St. Brown (DET) –  $6,900 @ CHI, Christian Kirk (JAX) – $5,900 @ KC, Stefon Diggs (BUF) – $8,300 v MIN, Diontae Johnson (PIT) – $5,800 v NO, Amari Cooper (CLE) – $6,500 @ MIA

Tight Ends

Greg Dulcich (DEN) – $3,400 @ TEN

It’s a bit surprising that Greg Dulcich’s salary remains so low at this point. He was on a bye last week but before that, he had scored double-digit DraftKings points in three straight games. Those three games are the first three games of Dulcich’s NFL career. In those three games, he’s played at least 60% of the snaps and ran at least 20 routes in all three of them. It’s a small sample size but Dulcich’s 17-game pace stats look something like this: 68 receptions, 1,031 receiving yards, and 5 touchdowns. He would be the TE6 on a per-game basis if he had played enough games to qualify. Not bad for a third-round rookie tight end on a team that has been very underwhelming. This week’s matchup is a good one. The Tennessee Titans have not been a good defense, especially against the pass. They’ve allowed the seventh-most DraftKings points to tight ends so far this year as well. This makes Dulcich one of the best Week 10 DraftKings plays.

Foster Moreau (LV) – $3,200 v IND

This definitely looks like a week to spend down at tight end. Between there not being many attractive value options at running back or wide receiver, the value has to come from somewhere. Foster Moreau looks like one of the best salary-saving options this week. There was a time not too long ago when Moreau was considered the premier tight end handcuff when there are usually no handcuffs at the position. This year, he hasn’t quite produced the same way when given the opportunity. Waller has been banged up this year and, as previously mentioned, has now been placed on IR along with Renfrow. This opens up a ton of playing time and opportunity for Moreau as well. This should be a good spot as the Indianapolis Colts defense is a bit banged up right now and this game is being played in a dome.

Others to Consider: Travis Kelce (KC) – $7,800 v JAX, Pat Freiermuth (PIT) – $4,200 v NO, Evan Engram (JAX) – $3,300 @ KC

Defense/Special Teams

In terms of choosing a defense/special teams, it’s the last spot I fill in every week. It’s pretty random but there are a few areas to gain an advantage. I aim to target the heavily favored teams, who usually play with a lead. This forces their opponent to throw it more often which can help lead to extra sacks and turnovers and hopefully a touchdown. Another aspect to target is turnover and sack-prone quarterbacks. My advice is to fill out the rest of your lineup first and then pick your favorite D/ST out of the remaining money.

My Tentative Cash Game Lineup

  • QB – Justin Fields
  • RB – Alvin Kamara
  • RB – Dameon Pierce
  • WR – Cooper Kupp
  • WR – Amon-Ra St. Brown
  • WR – Donovan People-Jones
  • TE – Foster Moreau
  • Flex – Mack Hollins
  • DST – Minnesota Vikings

Make sure to tune in next week to see the results from my Week 10 DraftKings plays and to see the best picks for Week 11. Best of luck to everyone and let’s all enjoy some football and win some money!

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