NFL Betting Predictions | Week 1 Sunday Late Slate And Sunday/Monday Night Football

NFL Betting Predictions

These NFL betting predictions highlight ‘everything you need to know’ before placing some bets before the NFL Evening Sunday Games and Sunday/Monday Night Football. Let’s dive right into these betting lines, spreads and over/under picks. 

Week 1 NFL Betting Predictions: Early Slate

Week 1 NFL Betting Prediction: Sunday Late Slate and Monday Night

Cleveland Browns @ Kansas City Chiefs (-6.0)

Arrowhead Stadium | Kansas City, Missouri 

Sunday, September 12, 2021; 4:25 PM EST

A little known secret to beat the Browns is for the opposing quarterback to get outside of the pocket to execute a quarterback run or find an open receiver. If Patrick Mahomes manages to do this in this game, you could see a huge game from Travis Kelce. Kevin Stefanski and the Browns best chance of winning is to try to have long possessions to keep the ball out of Patrick Mahomes’s hands. 

Pick: Chiefs win, cover spread

Over/Under: 53.0 [Pick: Over]

Green Bay Packers (-4.5) @ New Orleans Saints

TIAA Bank Field | Jacksonville, Florida

Sunday, September 12, 2021; 4:25 PM EST

The Saints are at a disadvantage after Hurricane Ida left a mess in New Orleans. The game will be played in Jacksonville now instead of the Superdome. Aaron Rodgers will be playing with a chip on his shoulder and he is poised and ready to light the scoreboard up. Jameis Winston has Alvin Kamara to get the ball to in open space but the Packers defense will prioritize slowing the superstar running back down.

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Pick: Packers win, cover spread

Over/Under: 50.0 [Pick: Over]

Miami Dolphins @ New England Patriots (-2.5)

Gillette Stadium | Foxborough, Massachusetts 

Sunday, September 12, 2021; 4:25 PM EST

The Patriots cut ties with Cam Newton after the preseason which has set Mac Jones up to start Week 1. This divisional matchup will be rough for Mac Jones and Tua Tagovailoa to get into a groove. This game should be close throughout. Bill Belichick will not let his rookie quarterback lose his first game.

Pick: Patriots win, cover spread

Over/Under: 43.5 [Pick: Under]

Denver Broncos (-2.5) @ New York Giants

MetLife Stadium | East Rutherford, New Jersey

Sunday, September 12, 2021; 4:25 PM EST

The Broncos have a top 10 defense in the NFL. The Giants have added Kenny Golladay in free agency and Kadarius Toney in the 2021 NFL Draft to help Daniel Jones in the receiving department. With Evan Engram and Saquon Barkley dealing with injuries that will keep them from being 100%, the Giants will need to ‘air it out’ to keep up in this game. Daniel Jones won’t have a ton of luck airing it out against a strong defense.

Pick: Broncos win, cover spread

Over/Under: 41.5 [Pick: Over]

Chicago Bears @ Los Angeles Rams (-7.5)

Sofi Stadium | Los Angeles, California

Sunday, September 12, 2021; 8:20 PM EST

Despite Justin Fields’s electric preseason, the Bears do not believe Andy Dalton has done enough to lose the job yet. Matt Stafford will be facing off against a team he has faced twice a year for over a decade. Adding a competent quarterback to Sean McVay’s system is going to strengthen the offense to the next level. 

Pick: Rams win, do not cover spread

Over/Under: 44.5 [Pick: Under]

Baltimore Ravens (-4.5) @ Las Vegas Raiders

Allegiant Stadium | Las Vegas, Nevada

Monday, September 13, 2021; 8:15 PM EST

This game has a tricky twist in the way it could play out. Jon Gruden likes to attack the quarterback, especially mobile quarterbacks. Look for Jon Gruden to put a spy linebacker or safety on Lamar Jackson for most of the game, which will force Jackson to either air it out or make mistakes. Look for this game to be low-scoring with the Raiders winning on Monday Night!

Pick: Raiders win outright

Over/Under: 51.5 [Pick: Under]

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